For simplicity one can think of the + class as having one extra base … — Francis Crick

For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the - class as having one too few.

Francis CrickScientist · English · 1916 – 2004

More from Francis Crick

Our object in the construction of the state is the greatest happiness of the whole, and not that of any one class. — Plato
In general, the art of government consists of taking as much money as possible from one class of citizens to give to another. — Voltaire
There is only one class in the community that thinks more about money than the rich, and that is the poor. The poor can think of nothing else. — Oscar Wilde
If poly A is added to poly U, to form a double or triple helix, the combination is inactive. — Francis Crick
Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap. — Francis Crick
If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it. — Francis Crick